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The International Journal of Radiation Oncology * Biology * Physics (IJROBP), known in the field as the Red Journal, publishes original laboratory and clinical investigations related to radiation oncology, radiation biology, and medical physics. Original contributions by leading scientists and researchers include experimental studies of combined modality treatment and relevant innovations in tumor sensitization, especially at the molecular level, normal tissue protection, including both precision avoidance and biochemical means, brachytherapy, particle irradiation, and tumor imaging. Technical advances related to dosimetry and conformal radiation treatment planning are also included.

James D. Cox, M.D., serves as the journal's Editor-in-Chief. He can be contacted at International Journal of Radiation Oncology * Biology * Physics, Department of Scientific Publications, Unit 1202, 1515 Holcombe Blvd., Houston, TX 77030; phone: (713) 792-6014; fax: (713) 794-1120; e-mail: ijrobp@mdanderson.org.

The IJROBP can be accessed online at its Web site, www.redjournal.org. Journal submissions and reviews: External link http://ees.elsevier.com/rob/.

Electronic Submissions and Correspondence

The IJROBP accepts submissions and correspondence electronically, and the Web-based system enables authors to track their submissions online. The entire review process and all written correspondence are also handled through this system. Author and reviewer tutorials are provided online, and 24-hour phone and e-mail help is available.

Authors must register on the Website with their e-mail address and other information to receive a password. Those who have previously reviewed a manuscript for the IJROBP may already be registered. Specific instructions for accessing and using the system can be found at www.redjournal.org. (Select the Submissions & Reviews button). Once the submission files are uploaded, the system automatically generates an electronic (PDF) proof, which is then used for reviewing. All correspondence, including editor decisions and requests for revisions, are by e-mail.

Journal Policies

Human and Animal Experimentation. When reporting on human subjects, please indicate in the text whether the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional or regional) and with the Helsinki Declaration of 1975, as revised in 2000. Patient anonymity must be ensured at all times; do not use patient names, initials, hospital numbers, or other identification in the manuscript, tables, or figures. In clinical photographs, identities of patients should be masked or otherwise cropped. Written consent forms from patients must accompany all photographs in which there is any possibility of identification of the patient. When reporting experiments on animals, please also indicate in the text that you followed the institution's or a national research council's guide for, or a national law on, the care and use of laboratory animals.

Conditions of Publication. It is a condition of publication that manuscripts submitted to the IJROBP have not already been published and will not be submitted simultaneously or published elsewhere. All manuscripts submitted to the IJROBP are subject to peer review, and only those that are of the highest scientific quality are accepted for publication.

Copyright Transfer. Authors are required to sign a copyright transfer form, which will accompany page proofs of the article. For details on copyright policy, please refer to Copyright Information at External link http://www.elsevier.com/authors.

Conflict of Interest Policy. The IJROBP adheres to the policy on conflict of interest promulgated by the International Committee of Medical Journal Editors, which states, in part, that "to prevent ambiguity, authors must state explicitly whether potential conflicts do or do not exist." (See Conflict of Interest Notification.) The complete policy can be accessed at the following Web site: www.icmje.org.

Authorship. According to the "Uniform Requirements" (see Journal Style and Guidelines), all persons designated as authors should qualify for authorship. Each author should have participated sufficiently in the work to take public responsibility for its content. Authorship credit should be based only on substantial contributions to (1) conception and design, or analysis and interpretation of data, and to (2) drafting the article or revising it critically for important intellectual content, and to (3) final approval of the version to be published. Conditions 1-3 must all be met. Participation solely in the acquisition of funding or the collection of data does not justify authorship. General supervision of the research group does not justify authorship. Any part of an article critical to its main conclusions must be the responsibility of at least one author.

In the case of corporate authorship, all members of the group must meet all criteria to justify authorship and inclusion in the byline. Those who do not meet these criteria should be listed (with their permission) in an Acknowledgments section.

The order of authorship must be agreed to by all co-authors before the manuscript is submitted for consideration. Any changes in authorship after submission of a manuscript must be explained in a letter to the Editor-in-Chief that is signed by all co-authors to indicate their consent to the change. These changes include the deletion and addition of authors as well as any change in the order of authors. Changes can be expected to delay publication.

Permissions. Written permission must be obtained by authors and submitted with the manuscript for the following:
  • permission of the publisher and/or copyright holder to reprint in theIJROBP any material that has been previously published, including figures, tables, and quotations; quotations must be accurate and fully credited.
  • permission for the use of personal communication and/or unpublished data; such communication must include the name, degrees of the person(s) with whom the author has communicated or obtained the data, and the month and year in which the information was obtained.
  • written consent forms from patients for all photographs in which there is any possibility of identifying the patient.

Permissions letters and forms must be uploaded separately from the manuscript and mentioned in the cover letter.

Online Publication. Articles that have been accepted for publication, set into page proof, and corrected by authors and editors are posted online before print publication under the "Articles in Press" section of theIJROBP's Web site, www.redjournal.org.

Journal Style and Guidelines

In addition to this Instructions to Authors, the IJROBP relies on the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals," (External link http://www.icmje.org/) and the American Medical Association Manual of Style, 9th ed.

Types of Manuscripts

Rapid Communication. Rapid communication manuscripts have been discontinued.

Editorials. Editorials are brief commentary, analysis, or opinion pieces about a published article or other topic of special interest. Both solicited and unsolicited editorials undergo review and should not exceed 1,500 words and 10 references.

Critical Reviews. Critical reviews are contributions from experts in the field and are solicited by or on behalf of the journal s Editor-in-Chief or Senior Editor for Critical Reviews. Before a critical review article is initiated, potential authors will be expected to complete and submit a financial disclosure. Authors with interest or questions regarding critical reviews should write to Lynn D. Wilson, M.D., M.P.H. (Senior Editor, Critical Reviews): Lynn.Wilson@yale.edu. Critical Review articles are limited to 6,500 words including references.

Correspondence. Letters to the editor must be brief and concise. Those with comments on a particular article should be submitted within 2 months of publication of the article; authors whose articles are being commented on are given the opportunity to reply and should do so within 2 months of the request. Letters must be limited to no more than 400 words and 10 references. Correspondence is reviewed by the Editor-in-Chief for possible inclusion in the journal. Letters and replies must be submitted electronically using the online system.

Book Reviews. Reviews of recently released books of interest to the journal's readers are published on a limited basis and must not exceed 700 words. Submissions should be made electronically using the online system under the category "Book Review." Queries and review copies of books should be sent directly to the book review editor, David S. Shimm, M.D., who will consider them for publication: dshimm@aol.com. or Raleigh Regional Cancer Center, 275 Dry Hill Road, Beckley, WV 25801.

Scientific Articles. The journal publishes scientific articles describing original laboratory and clinical investigations related to radiation oncology, radiation biology, and medical physics. Submissions are thoroughly reviewed for scientific originality, significance, relevance, and priority, and the topics must be of broad interest to the journal's readers. Only high-priority manuscripts that report cutting-edge science and that promise to have a strong impact on clinical practice are accepted. Articles must not exceed 5,000 words.

Controversy Articles. This section is devoted to an exchange on controversial topics that are of a higher profile than can be adequately dealt with in the Letters to the Editor section. The Editor-in-Chief, in conjunction with the Senior Editors, identifies topics that qualify for the feature. The section is accompanied by a commentary that introduces and explains the controversy.

Style for Scientific Articles

All material submitted to the journal must be typed double-spaced. Each page of a manuscript (except the title page, which is page 1) should be identified with the first author's last name and the page number in the top right-hand corner. This format should be used throughout the text, references, figure legends, and tables.

The text should have clearly marked levels of headers and follow the standard format of Abstract, Introduction, Methods and Materials, Results, and Discussion. The manuscript should be organized in the following sequence: title page, abstract, key words, text, references, and legends.

Manuscript Format

Text and tables must be submitted in Word format. Figures and tables must be in separate files. (See Figures and Tables sections.) Only standard abbreviations and acronyms should be used, and each one should be defined at its first use in the text.
Manuscripts must be thoroughly edited by an English language medical editor to be acceptable for publication.

Parts of a Scientific Article

Title Page. The title page should include a concise but informative title; a complete byline (see Authorship), including each author's full name and highest earned academic degree(s); each author's complete affiliation( s), including department(s), institution(s), city, state, and country; the name and complete mailing address, phone number, fax number, and e-mail address of the corresponding author (to whom all correspondence and reprint requests will be directed); and a shortened running title. Acknowledgment of grant or other financial support, meeting presentation, conflict of interest, or assistance with manuscript preparation or data collection can be included here or in an Acknowledgments section.

Conflict of Interest Notification. On the page that follows the title page under the heading "Conflicts of Interest Notification," please state explicitly whether any actual or potential conflicts of interest do or do not exist. Provide additional detail, as necessary, in the accompanying cover letter.

Abstract. The Abstract should have no more than 300 words and should be structured using the following subheadings: Purpose, Methods and Materials, Results, and Conclusions. These subheadings should not be used in abstracts for Critical Review articles; abstracs for Critical Reviews should just summarize the content of the article. The Abstract should reflect the content of the article and include the purpose of the study, the experimental design, the most important results, and an interpretation of the data, including the conclusion and any implications derived from the results.

Key Words. After the Abstract, provide five specific key words for indexing.

Introduction. The Introduction section should include the background and rationale for the study, a clear purpose or hypothesis statement, and a brief description of the experimental design.

Methods and Materials. The Methods and Materials section should describe the materials used and the experimental and statistical methods. Previously described methods should not be included, only cited, with significant modifications stated. Clinical studies should be identified as retrospective or prospective. Methods should not be included in the Results section or figure legends.

Results. The Results section should describe only the most important results of the study and include as little discussion as possible. Measures of statistical significance must be clearly indicated, and tables and figures should be cited in numerical order.

Discussion. The Discussion section should begin with a statement of the conclusions based on the study's findings and include an interpretation of the results in the context of other published studies. The study's limitations and implications should also be stated. The conclusions can be included in this section or presented separately under the heading "Conclusions." They should be clearly tied to the purpose of the study. Background information, methods, and results should not be repeated in detail in the Discussion.

References. The reference list must be typed double-spaced. References must be cited and numbered in consecutive numerical order as they first appear in the text and should be listed in consecutive numerical (not alphabetical) order in the References section. All bibliographic information must be complete and accurate. The author is responsible for the accuracy of all references. The following reference style must be used, and the author should also refer to the "Uniform Requirements" and the American Medical Association Manual of Style for other examples and conventions.

Journal references should be given in the following order: author(s) surnames and initials, that is, the names of the first three authors followed by et al.; article title (with subtitle if any), journal abbreviation in italics, year, volume number, part or supplement number, and inclusive page numbers. If the paper has been seen only in abstract form, this should be indicated at the end of the original reference by the addition of the word [Abstract]. Likewise, if the reference is to a volume with a supplement, the supplement number with the abbreviation [Suppl.] should be included. References to books must include the names of the authors, title, edition number, city of publication, publisher, and year. References to chapters in books must include the names of the editors and the chapter title after the name(s) of the author(s) and the book title. Examples of references using the AMA numbered style follow:
  1. Davis JT, Allen HD, Powers JD, et al. Population requirements for capitation planning in pediatric cardiac surgery. Arch Pediatr Adolesc Med 1996;150:257-259.
  2. Champlin RER, Feig SA, Ho WG, et al. Bone marrow transplantation for acute lymphoblastic leukemia in remission: Importance of extramedullary involvement [Abstract]. Blood 1982;60 (Suppl. 1):165a.
  3. Ringsven MK, Bond D. Gerontology and leadership skills for nurses. 2nd ed. Albany (NY): Delmar Publishers; 1996.
  4. Phillips SJ, Whisnant JP. Hypertension and stroke. In: Laragh JH, Brenner BM, editors. Hypertension: Pathophysiology, diagnosis, andmanagement. 2nd ed.NewYork:RavenPress; 1995. p. 465-478.

Figures. Each figure should be placed in a separate file and uploaded individually at submission. Please make sure that each figure is properly identified in the file. Figures should be consecutively numbered (1, 2, 3, etc.) as they appear in the text and must be accompanied by legends (See Figure Legends.). The author should include figures that enhance, not duplicate, textual information. Four-color figures may be submitted, but the author must assume all costs for separation and printing. Color figures are printed free of charge in the online version of articles. Lettering should be uniform and large enough to be easily read when reduced for publication. Patient anonymity must be ensured at all times; do not use patient names, initials, hospital numbers, or other identification in the figures or legends. In clinical photographs, identities of patients should be masked or otherwise cropped. Written consent forms from patients must accompany all photographs in which there is any possibility of identifying the patient. Unsuitable figures will be returned to the author for correction or substitution.

Previously published figures must be accompanied by written permission to reprint from the publisher and authors, with sources cited in the text.

Figures should be supplied in TIF or EPS format. All photographic images should be submitted at 300 dpi; all line art images should be submitted at 800 to 1,200 dpi. BMP, JPEG, and GIF file formats are unacceptable for publication, as are figures embedded in the manuscript document.

For further details in the preparation of artwork and the types of files that are acceptable for publication, please go to www.elsevier.com/locate/artwork.

Figure Legends. Complete, explanatory, and descriptive legends must be provided for all figures. The legends must correspond to the consecutively numbered figures and be typed double-spaced after the References section inside the manuscript document. All abbreviations or other letter designations used in a figure must be defined in the legend for that figure. Magnification and staining materials should be indicated. Acknowledgment of previously published material should be given in the legend, and the source should be included in the References section. (See Permissions.)

Tables. Tables should be placed in one separate file for uploading at submission, preferably in a Word document. Tables should be typed double-spaced on separate pages, and numbered consecutively, as well as cited in the text in numerical order. Each table number (1, 2, 3, etc.) should be followed by a brief, specific title. Table titles should be placed above each of their respective tables. The data should be self-explanatory and should supplement, not duplicate, the text. Previously published tables must be accompanied by written permission to reprint from the publisher and authors, with sources cited in the text. Acknowledgments to previously published material should be given in a footnote to the table, and the source should be included in the References section. (See Permissions.) All abbreviations used in the table must be defined in the footnotes. Footnotes should be ordered as they first appear in the table with the following standard symbols: ) *(asterisk), † (dagger), †† (double dagger),§ (section mark), || (parallel mark), ¶ (paragraph symbol), and # (number sign).

Supplementary Material. Authors are welcome to submit supplementary material and appendices at the time of e-submission. However, the Editor-in-Chief will determine whether the material is relevant enough to the content of the manuscript that it should be published with the manuscript. If not, the author will be told that the material will be posted on the Journal's website and a footnote will be added to the opening page of the article indicating that "Supplementary material or appendices for this article can be found at www.redjournal.org." It is recommended that authors indicate this Web site in the text where the material is cited and number the material as Table e1 or Figure e1, etc. Appendices should be numbered Appendix eI or eII, etc. While supplementary material and appendices will be reviewed, it will not be typeset or edited by the publisher.



Updated January 2010